Smoking and Alpha-1 Antitrypsin Deficiency (AATD)
"If you have AATD, you can develop COPD early in your life and it might progress more rapidly than usual, especially if you smoke. People with AATD who smoke might develop COPD symptoms in their 20s, while people with AATD who have never smoked are more likely to have symptoms over the age of 40. Without AATD, COPD symptoms don’t normally develop until you are over 50."
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